The One Step Drug of Abuse Test is a competitive immunoassay utilizing highly specific reactions between antibodies and antigens for the detection of multiple drugs and drug metabolites in human urine without the use of an instrument.
AMPHETAMINE(AMP 1000) also known as Speed, Whiz, Uppers, Dexies
Amphetamine is a Schedule II controlled substance available by prescription (Dexedrine?) and is also available on the illicit market. Amphetamines are a class of potent sympathomimetic agents with therapeutic applications. They are chemically related to the human body's natural catecholamines: epinephrine and norepinephrine. Acute higher doses lead to enhanced stimulation of the central nervous system and induce euphoria, alertness, reduced appetite, and a sense of increased energy and power. Cardiovascular responses to Amphetamines include increased blood pressure and cardiac arrhythmias. More acute responses produce anxiety, paranoia, hallucinations, and psychotic behavior. The effects of Amphetamines generally last 2-4 hours following use, and the drug has a half-life of 4-24 hours in the body. About 30% of
Amphetamines are excreted in the urine in unchanged form, with the remainder as hydroxylated and deaminated derivatives.
The AMP 1000 assay contained within the One Step Drug of Abuse Test yields a positive result when Amphetamines in urine exceed 1,000 ng/mL. This is the suggested screening cut-off for positive specimens set by the Substance Abuse and Mental Health Services Administration (SAMHSA, USA).
Amphetamines are detectable in urine using this drug test kit (AMP) for 2 to 6 days at a cut-off level of 1000 ng/ml.
BENZODIAZEPINES (BZO) also known as Benzos, Tranx
Benzodiazepines are medications that are frequently prescribed for the symptomatic treatment of anxiety and sleep disorders. They produce their effects via specific receptors involving a neurochemical called gamma aminobutyric acid (GABA). Because they are safer and more effective, Benzodiazepines have replaced barbiturates in the treatment of both anxiety and insomnia. Benzodiazepines are also used as sedatives before some surgical and medical procedures, and for the treatment of seizure disorders and alcohol withdrawal. Risk of physical dependence increases if Benzodiazepines are taken regularly (e.g., daily) for more than a few months, especially at higher than normal doses. Stopping abruptly can bring on such symptoms as trouble sleeping, gastrointestinal upset, feeling unwell, loss of appetite, sweating, trembling, weakness, anxiety and changes in perception. Only trace amounts (less than 1%) of most Benzodiazepines are excreted unaltered in the urine; most of the concentration in urine is conjugated drug. The detection period for the Benzodiazepines in the urine is 3-7 days. The BZO assay contained within the One Step Drug of Abuse Test yields a positive result when the Benzodiazepines in urine exceed 300 ng/mL.
Benzodiazepines are detectable in urine using this drug test kit (BZO) for 2 to 14 days (depending on the drug) at a cut-off level of 300 ng/ml.
COCAINE (COC 300) also known as Coke, Crack, Charlie
Cocaine is a potent central nervous system (CNS) stimulant and a local anesthetic. Initially, it brings about extreme energy and restlessness while gradually resulting in tremors, over-sensitivity and spasms. In large amounts, cocaine causes fever, unresponsiveness, difficulty in breathing and unconsciousness. Cocaine is often self-administered by nasal inhalation, intravenous injection and free-base smoking. It is excreted in the urine in a short time primarily as Benzoylecgonine. Benzoylecgonine, a major metabolite of cocaine, has a longer biological half-life (5-8 hours) than cocaine (0.5-1.5 hours), and can generally be detected for 24-48 hours after cocaine exposure.
The COC 300 assay contained within the One Step Drug of Abuse Test yields a positive result when the cocaine metabolite in urine exceeds 300 ng/mL. This is the suggested screening cut-off for positive specimens set by the Substance Abuse and Mental Health Services Administration (SAMHSA, USA).
Cocaine is detectable in urine using this drug test kit (COC) for 2 to 5 days at a cut-off level of 300 ng/ml.
MARIJUANA (THC 50) also known as Weed, Pot, Grass, Hash
THC (D9-tetrahydrocannabinol) is the primary active ingredient in cannabis (marijuana). When smoked or orally administered, THC produces euphoric effects. Users have impaired short term memory and slowed learning. They may also experience transient episodes of confusion and anxiety. Long-term, relatively heavy use may be associated with behavioral disorders. The peak effect of marijuana administered by smoking occurs in 20-30 minutes and the duration is 90-120 minutes after one cigarette. Elevated levels of urinary metabolites are found within hours of exposure and remain detectable for 3-10 days after smoking. The main metabolite excreted in the urine is 11-nor-D9-tetrahydrocannabinol-9-carboxylic acid (D9-THC-COOH). The THC 50 assay contained within the One Step Drug of Abuse Test yields a positive result when the concentration of D9-THC-COOH in urine exceeds 50 ng/mL. This is the suggested screening cutoff for positive specimens set by the Substance Abuse and Mental Health Services Administration (SAMHSA, USA)
The active ingredient of cannabis (THC or Tetrahydrocannabinol) is detectable using this drug test kit (THC) for typically 14 to 28 days for frequent use of the drug, or around 5 days for a one-off use, at a cut-off level of 50 ng/ml.
MDMA also known as Ecstasy, E, XTC, X
MDMA or Ecstasy (3-4-methylenedioxymethamphetamine) is a synthetic drug with amphetamine-like and hallucinogenic properties. Known as E, Adam, ecstasy, XTC, and X, MDMA often comes in tablet form. This is commonly considered to be a dance or 'rave' drug used by younger people. External physical symptoms of use include muscle tension, involuntary teeth clenching, nausea, blurred vision, rapid eye movement, faintness and chills or sweating. Please also be aware that higher doses of Ranitidine (a medication used to control stomach acid) has been known to give a positive result on numerous brands of Methamphetamine test kits. Please determine any recently taken medications prior to conducting the test. A genuine Methamphetamine or MDMA positive sample will frequently prove positive on the Amphetamine (AMP) test as well because Amphetamine is one of the breakdown products of those drugs.
MDMA, or Ecstasy is detectable in urine using this drug test kit (MDMA) for 2 to 6 days at a cut-off level of 1000 ng/ml.
METHADONE (MTD)
Methadone is a narcotic analgesic prescribed for the management of moderate to severe pain and for the treatment of opiate dependence (heroin, Vicodin, Percocet, Morphine). The pharmacology of Oral Methadone is very different from IV Methadone. Oral Methadone is partially stored in the liver for later use. IV Methadone acts more like heroin. In most states you must go to a pain clinic or a Methadone maintenance clinic to be prescribed Methadone. Methadone is a long acting pain reliever producing effects that last from twelve to forty-eight hours. Ideally, Methadone frees the client from the pressures of obtaining illegal heroin, from the dangers of injection, and from the emotional roller coaster that most opiates produce. Methadone, if taken for long periods and at large doses, can lead to a very long withdrawal period. The withdrawals from Methadone are more prolonged and troublesome than those provoked by heroin cessation, yet the substitution and phased removal of methadone is an acceptable method of detoxification for patients and therapists.4 The MTD assay contained within the One Step Drug of Abuse Test yields a positive result when the Methadone in urine exceeds 300 ng/mL.
Methadone is detectable in urine using this drug test kit (MTD) for 2 to 8 days at a cut-off level of 300 ng/ml
OPIATE (OPI) also known as Heroin, Smack, Dope, Junk
Opiate refers to any drug that is derived from the opium poppy, including the natural products, morphine and codeine, and the semi-synthetic drugs such as heroin. Opioid is more general, referring to any drug that acts on the opioid receptor. Opioid analgesics comprise a large group of substances which control pain by depressing the central nervous system. Large doses of morphine can produce higher tolerance levels, physiological dependency in users, and may lead to substance abuse. Morphine is excreted
unmetabolized, and is also the major metabolic product of codeine and heroin. Morphine is detectable in the urine for several days after an opiate dose. 4 The OPI 2000 assay contained within the One Step Drug of Abuse Test yields a positive result when the concentration of opiate exceeds the 2000 ng/mL cut-off or positive specimens set by the Substance Abuse and Mental Health Services Administration (SAMHSA, USA).
Use of Heroin is detectable in urine using this drug test kit OPI for 2 to 5 days at a cut-off level of 300 ng/ml. Other opiates (such as codeine in some pain medication and cough syrups) can also be detected, regardless of the detection method, so please determine any recently taken medications prior to conducting the test.
